Recherche

CCMR Paris Charles Foix

Études en cours (recherche clinique et en laboratoire)

  • Étude clinique transversale de caractérisation de état bucco dentaire de patients avec une maladie rare (Sjögren primitif - avec collection biologique de Salive - , mucoviscidose, maladie de Wilson).
  • Caractérisation des neutrophiles salivaires des patients atteints de Trisomie 21.
  • Étude de l'olfaction-gustation des patients atteints du syndrome de Sjögren.
  • Collection biologiques ORCELL: Mise en place d'une bio-banque tissu dur et cellules de la cavité orale.

Technologies à disposition

  • microCT
  • Histologie conventionnelle
  • Immunohistochimie et immunofluorescence
  • Imagerie multiplex
  • Culture cellulaire
  • Biologie moléculaire
  • Génétique
  • Tri cellulaire et FACS
  • Technique omics ... (accès aux plateformes de l'Institut Cochin)

Expertises

  • Inflammation et résorption osseuse
  • Édification dentaire
  • Étude des tissus durs et des tissus mous
  • Régénération des tissus durs et des tissus mous

Laboratoires partenaires

Collaboration internationale

  • Department of Developmental Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany.
  • Dental Stem Cell Biology Research Unit, Faculty of Dentistry, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Center of Excellence for Regenerative Dentistry and Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, 34 Henri Dunant Rd. Pathumwan, Bangkok, 10330, Thailand.
  • Department of Periodontics, Loma Linda University School of Dentistry, Loma Linda, CA, USA.
  • Rheumatology Department, Milton Keynes University Hospital, Milton Keynes, UK.
  • Rheumatology Department, University Hospitals Birmingham and University of Birmingham, Birmingham, UK.
  • Neuroscience and Ophthalmology Research Group, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

Publications

  • Andrique C, Bonnet AL, Dang J, Lesieur J, Krautzberger AM, Baroukh B, Torrens C, Sadoine J, Schmitt A, Rochefort GY, Bardet C, Six I, Houillier P, Tharaux PL, Schrewe H, Gaucher C, Chaussain C. Vasorin as an actor of bone turnover? J Cell Physiol. 2024 Mar 19. doi: 10.1002/jcp.31257. Epub ahead of print. PMID: 38504496.
  • Foguem C, Seror R, Gosset M. Chemosensory dysfunction in primary Sjögren's syndrome: a topical review. Clin Rheumatol. 2023 Jan;42(1):1-14. doi: 10.1007/s10067-022-06359-w. Epub 2022 Sep 5. PMID: 36063255; PMCID: PMC9443648.
  • Nocturne G, Gosset M. Pathologies inflammatoires des glandes salivaires [Inflammatory diseases of the salivary]. Rev Prat. 2023 Sep;73(7):747-750. French. PMID: 37796262.
  • Duong LT, Petit S, Kerner S, Clerc MM, Arnoult C, Nowwarote N, Osathanon T, Fournier BPJ, Isaac J, Ferré FC. Role of periosteum during healing of alveolar critical size bone defects in the mandible: a pilot study. Clin Oral Investig. 2023 Aug;27(8):4541-4552. doi: 10.1007/s00784-023-05079-y. Epub 2023 Jun 1. PMID: 37261496.
  • Danvers P, Saide J, Decup F, Seror R, Belkhir R, Gosset M. Analysis of the dental care queries in the "Mouth-Nose" discussion forum of the French association of patients with Gougerot-Sjögren's syndromes and dryness. BMC Oral Health. 2022 Sep 22;22(1):418. doi: 10.1186/s12903-022-02450-5. PMID: 36131279; PMCID: PMC9494845.
  • Louvet L, Lenglet G, Krautzberger AM, Mentaverri R, Hague F, Kowalewski C, Mahtal N, Lesieur J, Bonnet AL, Andrique C, Gaucher C, Gomila C, Schrewe H, Tharaux PL, Kamel S, Chaussain C, Six I. Vasorin plays a critical role in vascular smooth muscle cells and arterial functions. J Cell Physiol. 2022 Oct;237(10):3845-3859. doi: 10.1002/jcp.30838. Epub 2022 Jul 26. PMID: 35892191; PMCID: PMC9796581.
  • Collignon AM, Vergnes JN, Germa A, Azogui S, Breinig S, Hollande C, Bonnet AL, Nabet C. Factors and Mechanisms Involved in Acquired Developmental Defects of Enamel: A Scoping Review. Front Pediatr. 2022 Feb 24;10:836708. doi: 10.3389/fped.2022.836708. PMID: 35281236; PMCID: PMC8907975.
  • Genet L, Jalladaud M, Seror R, Gosset M. Plasma cell gingivitis, an underestimated condition in patients with Sjögren's syndrome? Clin Exp Rheumatol. 2021 Nov-Dec;39 Suppl 133(6):225. doi: 10.55563/clinexprheumatol/g1ll8c. Epub 2021 Apr 21. PMID: 33886456.
  • Seror R, Rauz S, Gosset M, Bowman SJ. Disease activity and patient reported outcome measures in Sjögren's - what are the best tools to evaluate? Rheumatology (Oxford). 2021 Aug 2;60(8):3528-3539. doi: 10.1093/rheumatology/kez201. PMID: 31236580.